The paper deals with the effect of temperature and strain rate to microstructure evolution and final hardness of 33NiCrMoV15 steel after the simulation of the deformation process on real samples using of dilatometer DIL805D.  The main goal of the simulation is the evaluation of Peak Stress – deformation resistance for different deformation temperatures and rates. Measured values are also processed by regression analysis to define the mathematical model of the monitored dependency. Examined steel is high strength middle alloyed steel with an optimal level of plastic properties used for high loaded parts including howitzers and tanks gun barrels.